Focus on... Magali Richard (TIMC - BCM)

on the February 6, 2020

Magali Richard was a Junior Chair in the Grenoble Alpes Data Institute. She is involved in the WP2 Data Science for Life Sciences.
Magali Richard is an expert in computational genetics. After a thesis in genetics and neurobiology of the nematode C. elegans under the supervision of Jean-Louis Bessereau at the Ecole Normale Supérieure in Paris, she joined the group of Gael Yvert at the Ecole Normale Supérieure in Lyon to study genetic architecture of regulatory networks and adaptability in a dynamic environment, in the yeast S. cerevisiae. In 2017, she joined the BCM team to start a research theme on cancer analysis and modeling, in collaboration with Daniel Jost.

Magali was a Junior Chair at the Grenoble Alpes Data Institute. She was then recruited as a CNRS researcher in the interdisciplinary section CID51 "modeling of biological systems". Her project is to contribute to the understanding of the fundamental mechanisms of life by proposing an interdisciplinary approach based on the statistical analysis of biological data. She is particularly interested in the following questions: How to extract robust and specific information from biological data of various natures and origins? How does the molecular information of a biological entity (cell, tissue, organism, etc.) affect its composition and its environment?

From multi-omic biological data collected on cancer patients, Magali Richard is developing statistical models allowing a better understanding of the processes implemented during tumorigenesis. An example of a method that the researcher has developed concerns the personalized analysis of differential expression. This method makes it possible to determine which genes are differentially expressed, in each patient, in an individualized manner. Magali Richard now aims to characterize cellular heterogeneity in the context of lung cancer. To do this, she works in close collaboration with the GIPSA-lab, the IAB and the CHU-GA. Co-funded by EIT Health and the Grenoble Alpes Data Institute, she is also leading a European project dedicated to the organization and dissemination of data challenges on health data. Finally, together with Florian Privé, she contributed to the development of the Grenoble R community, in particular by organizing collaborative sessions one Thursday per month. Matthieu Rolland took over for the year 2019-2020.

Published on February 17, 2020